Jarrow Formulas Milk Thistle Standardized Silymarin Extract 30:1 Ratio, 150 mg per Capsule, 200 Gelatin Capsules


Standardized Silymarin Extract 30:1Jarrow FORMULAS Milk Thistle (Silybum marianum) 30:1 concentrate is standardized to contain 80% total Milk Thistle seed flavonoids, including the important Silymarin fractions isosilybinins A and B, silybinins A and B, silychristin and silydianin.This particular group of flavonoids, collectively known as Silymarin, supports liver function by raising protective glutathione levels.

Jarrow Formulas Milk Thistle, 150mg, 200 Capsules
At a Glance:
  • Beneficial for maintenance of the liver, the main detoxifying organ of the body*
  • Provides compounds that boost the body’s antioxidant system*
  • An important addition to detoxification regimens and an excellent tonic for anyone under stress*
  • Supports glutathione, one of the primary antioxidants found in the body*
Jarrow Formulas Milk Thistle, 150mg, 200 Capsules Product Shot

Beneficial for maintenance of the liver, the main detoxifying organ of the body*.

Jarrow Formulas Milk Thistle, 150mg, 200 Capsules Product Shot

Supports glutathione, one of the primary antioxidants found in the body*.
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An Ancient Herb

The Greek herbalist Dioscorides catalogued milk thistle in his list of healing plants for liver conditions, improving bile flow and stimulating digestion.* The Roman author Pliny was of a similar opinion. Indeed, milk thistle (Silybum marianum) extracts have been used as traditional herbal remedies for almost 2000 years and milk thistle is now extensively cultivated as a healing herb. This is especially true in Germany, where milk thistle is quite popular. Despite its distinctive prickly leaves and milky sap, milk thistle is sometimes confused with a different plant known as blessed or holy thistle (Cnicus benedictus).

Today, milk thistle extracts are among the most popular and the best researched of all herbs. Yet, this herb had largely become forgotten by the mid-20th Century. It was barely mentioned in the United States Dispensatory of 1947, and the most common folk use outside of Central Europe was to improve lactation.

Modern research has focused on bile production and liver function. German scientists have produced an extract called silymarin, which has a variety of liver-protectant properties.* The active principles normally constitute only 1-4 percent of the total plant, so it is necessary to concentrate the extract extensively to provide benefits. Jarrow Formulas Milk Thistle provides just such a potent concentrate.

Special Antioxidant Benefits

Silymarin refers to three active flavonoid components of milk thistle: primarily silybin with smaller amounts of silydianin and silychristin. This trio neutralizes toxins and improves liver function.* Its action rests primarily upon the ability to inhibit production and activity of hepatotoxic (liver toxic) compounds.* More recent evidence indicates that it benefits the health of several other organs as well.*

The liver is the primary organ for detoxification. Many toxins are either free radicals, or encourage free radical production and may subsequently interfere with the liver’s defenses against free radicals. As a potent antioxidant, silymarin intervenes in free radical generation and protects against many reactive oxygen species.* In some measurement systems, silymarin is ten times more effective than vitamin E in preventing unwanted oxidation. The extract also increases the liver’s content of the antioxidant enzyme glutathione (GSH) by ~35 percent, and increases the levels of the body’s major antioxidant enzyme, superoxide dismutase (SOD).* Silymarin also modulates the actions of lipoxygenase in the liver.* Lipoxygenase acts upon polyunsaturated fatty acids to produce pro-inflammatory compounds called leukotrienes, which cause damage to liver cell membranes.

Silymarin is active against all of these assaults upon liver cell integrity and function. It therefore has direct and indirect antioxidant benefits by elevating the body’s own defenses. Research has shown that milk thistle extracts also significantly enhance cellular immune biomarkers.*

Supporting Liver Regeneration, Bile Solubility

The liver is capable of extensive self-regeneration, but silymarin can even markedly increase this ability to replace damaged cells.* There is also some suggestion that silymarin stimulates protein synthesis in the liver.* Nevertheless, silymarin does not encourage malignant liver cell growth.* Growing evidence suggests that silymarin has protective properties to the kidneys that mirror those in the liver.*

Classically, milk thistle is associated with improved digestion and bile production.* These are important functions of the liver and their impairment can lead to undesirable outcomes in the body. Clinical trials have supported this traditional employment of the herb. The extract can increase bile solubility and possibly help guard against stone formation.*

Bioavailability

Silymarin exhibits poor solubility in water. Delivery in the form of teas provides less than 10 percent of total activity. Older studies demonstrating silymarin as a bile flow-inducer used alcoholic tinctures rather than the water-based preparations commonly sold today.

Only 20-50 percent of silymarin is assimilated from the gastrointestinal tract at any given time. Thus, an effective milk thistle supplement needs to be highly concentrated, like Jarrow Formulas Milk Thistle, to provide a physiologically significant amount. According to the German monograph covering milk thistle, 12-15 grams of the crude herbal extract provides 200-400 mg silymarin. This is equivalent to the amount delivered by only 3 capsules of Jarrow Formulas Milk Thistle.

About Jarrow Formulas

Jarrow Formulas’ complete line of over 350 nutritional products includes vitamins, minerals, probiotics, standardized herbal concentrates, amino acids, enzymes and enteral nutrition products. Customers can be assured of purity, value and potency when choosing these products.

What’s in the Box

Jarrow Formulas Milk Thistle, 150mg, 200 Capsules.

FDA Disclaimer

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$ 11.91

Comments

  1. Steve Olson says
    42 of 44 people found the following review helpful
    5.0 out of 5 stars
    Milk Thistle part of my pro-active plan for long term health, August 8, 2012
    By 
    Steve Olson
    (REAL NAME)
      

    This review is from: Jarrow Formulas Milk Thistle Standardized Silymarin Extract 30:1 Ratio, 150 mg per Capsule, 200 Gelatin Capsules (Health and Beauty)

    Milk thistle is an excellent way to prevent liver disease and damage, and high cholesterol. I have a family history of both so I do everything I can to prevent something irreversible from happening.

    Milk thistle is a core piece of my health prevention routine. I also take TUDCA, FREE Milk Thistle Powder 25 Grams + TUDCA Powder (Tauroursodeoxycholic) 5 Grams which is a lesser known yet more powerful version of milk thistle. The Jarrows Formula is excellent and I still have a bottle in my cabinet, although I’ve been more turned onto powder supplements in general just because their ability to more fully absorb into the bloodstream.

    I for one, will not wait for something terrible to happen before I start taking a pro-active approach to my health although I know this is the case for many people. TUDCA has actually been shown to reverse liver damage although there is nothing better than prevention of course. No matter where your health is, do your research, talk to your doctor and look into such supplements as TUDCA and Milk thistle. Best of luck!

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  2. S. Ferrell says
    28 of 28 people found the following review helpful
    5.0 out of 5 stars
    Lowered liver enzymes, July 19, 2012
    By 
    S. Ferrell (Western USA) –
    (REAL NAME)
      

    Amazon Verified Purchase(What’s this?)
    This review is from: Jarrow Formulas Milk Thistle Standardized Silymarin Extract 30:1 Ratio, 150 mg per Capsule, 200 Gelatin Capsules (Health and Beauty)

    I had high liver enzymes for the last 8 years. Doctors did not find out what was causing it. I found this product and took it for 6 month at 1200mg a day. Just had the blood work done and my liver function tests were in the normal range for the first time in 8 years. It worked for me..

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  3. Blasty LaRue says
    18 of 19 people found the following review helpful
    5.0 out of 5 stars
    Good Stuff, September 14, 2012
    By 

    This review is from: Jarrow Formulas Milk Thistle Standardized Silymarin Extract 30:1 Ratio, 150 mg per Capsule, 200 Gelatin Capsules (Health and Beauty)

    Great product and if you are a drinker over the age of 35, you really should be taking Milk Thistle. I take 2 x 150 mg pills in the morning and 2 x 150 mg pills at night. Don’t bother with teas and drops and so forth, this is just as effective and a lot easier and a cheaper too. Just make sure whatever Milk Thistle you use lists the Silymarin content. This product contain 80% total Milk Thistle seed flavonoids, including the important Silymarin fractions isosilybinins A and B, silybinins A and B, silychristin and silydianin. For just normal maintenance you should be around 250 mg – 500 mg per day. So, if you take 4 x 150 mg pills a day, that is 80% x 600 mg total = 480 mg. Anymore than that for a normal healthy person is unnecessary but not harmful.

    I started taking this about 18 months ago and after about 4 months I noticed that my hangovers were a lot milder. Now, after a moderate night of drinking (6 or 8 drinks) I have absolutely no hangover at all and have no problem getting up at 6:00 AM and going to work the next day. Before I started the Milk Thistle supplement, I would have a pretty noticeable hangover the next day after 6 drinks and there was no way I could drink more than 2 or 3 beers if I had to work the next day. Now, after a heavy night of drinking (12 – 14 drinks) I’ll feel a little rough the next morning for a few hours, but not crippled like before, and the hangover burns off by noon or 1:00 PM. Before I started the Milk Thistle, if I drank a 12-pack I would be destroyed and laying in bed the next day until dinner time and in horrendous pain. This stuff is great! Seriously, it is almost like when I was 22 years old again.

    Not a magic cure for hangovers, but it honestly knocks the intensity down about 70%. This really saved me the last time I went to Vegas. The other two guys I went with (who are 10 years younger than me) were completely crippled and in bed the entire 2nd day of the trip and couldn’t even drink the 2nd night. I was up at 1:00 PM (went to bed at 5:00 AM after drinking about 20 hard liquor drinks including 151 and some rot gut gin martinis) and was drinking beer at 3:00 PM. Did I feel 100%? Oh hell no, but I was able to chase the rest of the hangover away with a few microbrews and a cheeseburger while these guys were still dry heaving at the Black Jack table.

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