Jarrow Formulas Ubiquinol QH-Absorb, 100 mg, 120 Softgels


Ubiquinol is the reduced (active antioxidant) state of Co-Q10, the form produced by our cells and is significantly better absorbed as a supplement, particularly as we age. Jarrow FORMULAS QH-absorb is a proprietary enhanced stability formula, which has been clinically shown in humans to increase Co-Q10 levels up to 777% (6.14x) over baseline at 300 mg per day intake.

Ubiquinones are a series of homologous molecules that possess a quinone active center and an unsaturated fatty tail. Ubiquinones are so named because they are widely distributed (i.e. ubiquitous) in nature and throughout the human body. Structurally they are very similar to the menaquinones, like vitamin K2. The quinone group is like a courier for protons and electrons, which is the critical property that allows ubiquinones to act as antioxidants and as important intermediates in energy generation. The fatty tail is composed of isoprenoid subunits, which are five carbon building blocks that help all living things biosynthesize critical components like immune modulators, essential oils and hormones. The number of isoprenoid units in the fatty tail is often denoted in the name of specific ubiquinones. For instance, ubiquinone-10 is made from ten isoprenoid units. Ubiquinone-10 (aka CoQ10, coenzyme Q10, Q) is more commonly referred to as just “ubiquinone.” This is because it is the most prevalent ubiquinone in almost all mammals, including humans.

Jarrow Formulas QH-Absorb, 100mg, 120 Softgels
At a Glance:
  • The active antioxidant form of CoQ10
  • Supports heart function and antioxidant status*
  • Utilizes the Q-absorb natural, proliposomal delivery system for enhanced absorption
  • Designed for those who seek the superior absorption of ubiquinol (QH) for cardiovascular and antioxidant health*
  • Particularly useful to older consumers who may not activate
  • CoQ10 sufficiently or whose levels may be very low*
Jarrow Formulas QH-Absorb, 100mg, 120 Softgels Product Shot

Supports heart function and antioxidant status*. View larger.

Jarrow Formulas QH-Absorb, 100mg, 60 Softgels Product Shot

Utilizes the Q-absorb natural, proliposomal delivery system for enhanced absorption. View larger.

Sustainable

Concern about CoQ10 levels is especially important due to concern that cholesterol-lowering drugs (statins) work by inhibiting an enzyme that is also responsible for CoQ10-ubiquinol biosynthesis. As a result, anyone taking statins may have reduced levels of CoQ10-ubiquinol.

What is Ubiquinol?

Ubiquinone and ubiquinol (aka ubiquinol-10, CoQ10-H2, QH, “reduced” CoQ10) are intimately related, as their names suggest. Inside the body, Q (ubiquinone) can only achieve its important functions in energy production , cardiovascular health and antioxidant protection with the help of ubiquinol (QH).* In fact, all of the benefits that have been attributed to CoQ10 necessitate QH involvement. The two do their work by shuttling electrons and protons back-and-forth, cyclically transforming from Q to QH and back again. In energy production, CoQ10 facilitates electron transfer within mitochondrial membranes to produce ATP, the body’s energy currency.* For antioxidant protection, QH is the “active antioxidant” form of CoQ10. This means that Q that has not been converted to QH is inactive as an antioxidant. Perhaps this explains why circa 80-95 percent of total CoQ10 exists as QH in the blood and in healthy tissues that require its antioxidant function.*

Is Taking QH Better Than Taking Q?

CoQ10 is critically obtained from the diet, but it appears that absorption of Q may entail conversion to QH. This conversion occurs as early as in the enterocytes, the absorptive cells in the intestine, and may facilitate the absorption process. Also under normal conditions there are enzymes that help regenerate QH from Q, in the body. Unfortunately, aging and illness can lead to both a reduced ability to regenerate QH because of decreased enzyme activity and a decreased ability to absorb Q itself, possibly for the same reason.

After about age 45, total Q levels and QH levels tend to decline in various critical tissues. Some physicians have even started to use blood and tissue ratios of QH to Q as a biomarker for age- and health-related oxidative stress. So it may not come as a surprise that taking QH can provide benefits that surpass those obtained from taking standard Q. But where’s the evidence?

QH-absorb Clinical Research

Eleven young, healthy adults ingested 100 mg of QH-absorb with food three times daily (100 mg, t.i.d.) for fourteen days. Blood levels of total CoQ10, oxidized CoQ10 (Q) and reduced CoQ10 (QH) were measured at baseline and after fourteen days. This regimen of QH-absorb consumption resulted in a 777 percent mean increase of total CoQ10 levels compared to baseline and a 100 percent increase in plasma QH levels, the “active antioxidant” form of CoQ10.

Two conclusions can be drawn from these study results. First, it appears that even young, healthy individuals can achieve benefits from taking ubiquinol (reduced CoQ10) from QH-absorb that surpass taking Q alone. Previously, it was presumed that only older individuals would benefit from taking QH-absorb as it is known that starting about the age of 40, QH levels begin to decrease in the body. Second, the 777 percent increase of total CoQ10 levels measured after taking QH-absorb is more than double the levels achieved by even the best Q supplements. This suggests QH-absorb is at least twice as efficient in raising blood CoQ10 levels.*

Ubiquinol (QH) is Safe

Scientists have understood the value of QH for decades. It has just taken that long to figure out a way to stabilize QH so it can be formulated into a nutritional supplement product. Toxicity studies have shown little concern with taking QH directly, even at high doses. Plasma QH levels appear to plateau after two to four weeks of daily ingestion and then return near to baseline two weeks after daily ingestion is discontinued. It also appears that supplementation with QH does not reduce CoQ10 biosynthesis in the body.

Jarrow Formulas QH-absorb is made with ubiquinol (QH) the more bioavailable, active-antioxidant form of CoQ10. It utilizes the Q-absorb natural, proliposomal delivery system for enhanced absorption beyond that of QH alone.

About Jarrow Formulas

Jarrow Formulas’ complete line of over 350 nutritional products includes vitamins, minerals, probiotics, standardized herbal concentrates, amino acids, enzymes and enteral nutrition products. Customers can be assured of purity, value and potency when choosing these products.

What’s in the Box

Jarrow Formulas QH-Absorb, 100mg, 120 Softgels.

FDA Disclaimer

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$ 39.97

Comments

  1. Nandasiri Samarakone says
    27 of 28 people found the following review helpful
    5.0 out of 5 stars
    Valuable supplement, February 11, 2012
    By 
    Nandasiri Samarakone (California) –
    (REAL NAME)
      

    This review is from: Jarrow Formulas Ubiquinol QH-Absorb, 100 mg, 120 Softgels (Health and Beauty)

    I have found that CoQ10 supplementation helps maintain my general energy levels. Its not a caffeine type rush, rather a realization that you are walking more briskly and are more alert during the working day without the extreme tiredness and the end of the day or on weekends.

    A dose of 100 mg / day ( 1 capsule )seems to be the base level for me to experience this effect. On rare occasions I find it beneficial to increase it to 2 capsules.

    I have tried Qunol ( high absorption CoQ10 )in the past and found it to work well. Decided to switch to Ubiquinol the more readily bio available form as a number of studies suggests it raises blood plasma levels more quickly and that as we age the unreduced form tends not to be broken down as efficiently.

    I am not here to endorse either. I find that both work for me.

    Bottom line: Suggest anyone over the age of 50 look into CoQ10 or Ubiquinol supplementation as a way of improving their general energy levels. The fact that there could be several other potential benefits[…] is even more reason not to overlook this supplement. My own findings are that this supplement, Krill oil, Astaxanthin and Vitamin D are all valuable.

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  2. Jenn "Jenn" says
    22 of 24 people found the following review helpful
    5.0 out of 5 stars
    Jarrow great quality and good price., May 11, 2010
    By 
    Jenn “Jenn” (AZ United States) –

    Amazon Verified Purchase(What’s this?)

    I have chosen Jarrow for years for their product quality/prices. I chose soft gels as they are easy to swallow and are absorbed quickly.

    I chose the ubiquinol form of Co-Q10 over the standard form (ubiquinone) for reasons explained by Jarrow including that the standard form is “less efficient in some individuals, based on age or genetics.” and that “Ubiquinol also has superior bioavailability to ubiquinone, as demonstrated in clinical trials”.

    Edit Nov 2012: I just saw Dr. Weil (on Dr. Oz Season 4 Episode 49) say he prefers gel form because it absorbs better and he also said they should be taken with a meal that contains fat as it is fat soluble and it therefore needs fat to be absorbed.

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  3. 13 of 13 people found the following review helpful
    5.0 out of 5 stars
    Take IT!, November 4, 2011
    By 
    j-fit

    Amazon Verified Purchase(What’s this?)
    This review is from: Jarrow Formulas Ubiquinol QH-Absorb, 100 mg, 120 Softgels (Health and Beauty)

    One of those supplements that should be a part of your health stack, especially if over the age of 35 or taking statins.

    The ubiquinol form is superior than regular CoQ10, so while per pill is more expensive, your body will utilize a higher amount of it.

    We also give these to our Great Danes since they are known to have heart problems.

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